Publications

Papers & preprints

Peer-reviewed articles, reviews and preprints, generated straight from a BibTeX file — the complete, up-to-date record lives on Google Scholar.

Review Preprint

2026

  1. Cross-regulation of [2Fe–2S] cluster synthesis by ferredoxin-2 and frataxin

    K. Want, H. Gorny, E. Turki, M. Noiray, B. Monfort, R. Mor-Gautier, T. Tubiana, E. Jullian, V. Monnier, B. D’Autréaux

    Nature 649(8097), 721–728 (2026)

  2. Functional study of two flexible regions of the hepatitis E virus ORF1 replicase

    L. Mézière, S. Fieulaine, C. Montpellier, M. Ferrié, T. Tubiana, G. Arias, S. Bressanelli, L. Cocquerel, C.-M. Aliouat-Denis

    PLOS ONE 21(3), e0343555 (2026)

  3. ZDHHC17–Mediated Palmitoylation of Hepatitis E Virus ORF3 Protein Regulates Vectorial Trafficking in Polarized Epithelial Cells

    P. Bröscky, C. Syren, D. Ge, L. Kostrykin, A. Piras, Z. Engels, A. Freistaedter, H. Chi, P. Jordan, C. Funaya, K. Rohr, S. Tiwari, T. Tubiana, A. Pichlmair, V. Thi

    bioRxiv (2026)

    Preprint

  4. A novel dimerization site in non-structural protein 5A of hepatitis C virus regulates viral replication fitness

    P. Rothhaar, T. Tubiana, C. Förster, G. Arias, T. Arand, N. Schäfer, P. Ralfs, C. Heuss, A. Piras, A. Pichlmair, X. Hanoulle, S. Bressanelli, V. Lohmann

    PLOS Pathogens 22(8), e1014239 (2026)

  5. 4’-fluorouridine is a potent inhibitor of Oropouche virus in vitro and in animal infection models

    M. Ferrié, M. Darmuzey, I. Tarillon, T. Tubiana, M. Khan, T. Roskams, B. Weynand, D. Thal, N. Cremers, S. Hendrickx, K. Donckers, T. Portal, B. Vanmechelen, V. Lemmens, J. Rocha-Pereira, C. Castilletti, P. Mombaerts, S. Bressanelli, M. Laporte, H. Malet, J. Neyts

    bioRxiv (2026)

    Preprint

2025

  1. Structural characterization of the ACDC domain from ApiAP2 proteins, a potential molecular target against apicomplexan parasites

    M. Le Berre, T. Tubiana, P. Reuterswärd Waldner, N. Lazar, I. Sierra-Gallay, J. Santos, M. Llinás, S. Nessler

    Acta Crystallographica Section D: Structural Biology 81(1), 38–48 (2025)

  2. Integrin beta 1 facilitates non-enveloped hepatitis E virus cell entry through the recycling endosome

    R. Fu, P. Jordan, Z. Engels, J. Weihs, J. Mürle, H. Chi, S. Lara, B. Helm, M. Klöhn, J. Hu, A. Freistaedter, T. Boettler, M. Binder, U. Klingmüller, E. Steinmann, P.-Y. Lozach, T. Tubiana, S. Lemon, V. Dao Thi

    Nature Communications 16(1), 5403 (2025)

  3. Structural biology of single-stranded, positive-sense RNA viruses in the age of accurate atomic-scale predictions of protein structures

    S. Bressanelli, S. Fieulaine, T. Tubiana

    Virology 608, 110546 (2025)

    Review

  4. Hepatitis C virus NS3 helicase contributes to (−) strand RNA synthesis

    P. Ralfs, S. Bressanelli, L. Günter, A. Gabel, P. Rothhaar, K. Price, T. Tubiana, M. Munschauer, D. Frick, V. Lohmann

    Nature Communications 16(1), 8006 (2025)

  5. The hepatitis E virus capsid protein ORF2 counteracts cell-intrinsic antiviral responses to enable persistent replication in cell culture

    A.-K. Mehnert, S. Stegmaier, C. Alvarez, E. Toprak, V. Magalhães, C. Siebenkotten, J. Hu, A. Costa, D. Kirrmaier, M. Knop, X. Wu, T. Tubiana, C. Herrmann, M. Binder, V. Thi

    PLOS Pathogens 21(9), e1013516 (2025)

  6. The hepatitis E virus capsid protein ORF2 counteracts cell-intrinsic antiviral responses to enable persistence in hepatocytes

    A.-K. Mehnert, S. Stegmaier, C. Ramirez, V. Magalhães, C. Siebenkotten, J. Hu, A. Costa, D. Kirrmaier, M. Knop, X. Wu, T. Tubiana, C. Herrmann, M. Binder, V. Thi

    bioRxiv (2025)

    Preprint

2024

  1. A Perspective on the Prospective Use of AI in Protein Structure Prediction

    R. Versini, S. Sritharan, B. Aykac Fas, T. Tubiana, S. Aimeur, J. Henri, M. Erard, O. Nüsse, J. Andreani, M. Baaden, P. Fuchs, T. Galochkina, A. Chatzigoulas, Z. Cournia, H. Santuz, S. Sacquin-Mora, A. Taly

    Journal of Chemical Information and Modeling 64(1), 26–41 (2024)

  2. Studying self-assembly of norovirus capsid by a combination of in silico methods

    J.-C. Carvaillo, T. Tubiana, S. Detchanamourtty, S. Bressanelli, F. Silva, Y. Boulard

    bioRxiv (2024)

    Preprint

  3. Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex

    R. Ruedas, R. Vuillemot, T. Tubiana, J.-M. Winter, L. Pieri, A.-A. Arteni, C. Samson, S. Jonic, M. Mathieu, S. Bressanelli

    Journal of Structural Biology 216(2), 108095 (2024)

  4. Nonstructural protein 4 of human norovirus self-assembles into various membrane-bridging multimers

    A. Royet, R. Ruedas, L. Gargowitsch, V. Gervais, J. Habersetzer, L. Pieri, M. Ouldali, M. Paternostre, I. Hofmann, T. Tubiana, S. Fieulaine, S. Bressanelli

    Journal of Biological Chemistry 300(9) (2024)

  5. The AP-1 adaptor complex is essential for intracellular trafficking of the ORF2 capsid protein and assembly of Hepatitis E virus

    M. Ferrié, V. Alexandre, C. Montpellier, P. Bouquet, T. Tubiana, L. Mézière, M. Ankavay, C. Bentaleb, J. Dubuisson, S. Bressanelli, C.-M. Aliouat-Denis, Y. Rouillé, L. Cocquerel

    Cellular and Molecular Life Sciences 81(1), 335 (2024)

2023

  1. \textitDe novo modelling of HEV replication polyprotein: Five-domain breakdown and involvement of flexibility in functional regulation

    S. Fieulaine, T. Tubiana, S. Bressanelli

    Virology 578, 128–140 (2023)

  2. Hepatitis E virus RNA replication polyprotein: taking structural biology seriously

    S. Fieulaine, T. Tubiana, S. Bressanelli

    Frontiers in Microbiology 14 (2023)

  3. Ensemble-based molecular docking and spectrofluorometric analysis of interaction between cytotoxin and tumor necrosis factor receptor 1

    N. Misuan, S. Mohamad, T. Tubiana, M. Yap

    Journal of Biomolecular Structure and Dynamics 41(24), 15339–15353 (2023)

2022

  1. Dissecting peripheral protein-membrane interfaces

    T. Tubiana, I. Sillitoe, C. Orengo, N. Reuter

    PLOS Computational Biology 18(12), e1010346 (2022)

2021

  1. Membrane models for molecular simulations of peripheral membrane proteins

    M. Moqadam, T. Tubiana, E. Moutoussamy, N. Reuter

    Advances in Physics: X 6(1), 1932589 (2021)

    Review

2019

  1. Septin 9 has Two Polybasic Domains Critical to Septin Filament Assembly and Golgi Integrity

    M. Omrane, A. Camara, C. Taveneau, N. Benzoubir, T. Tubiana, J. Yu, R. Guérois, D. Samuel, B. Goud, C. Poüs, S. Bressanelli, R. Garratt, A. Thiam, A. Gassama-Diagne

    iScience 13, 138–153 (2019)

2018

  1. TTClust: A Versatile Molecular Simulation Trajectory Clustering Program with Graphical Summaries

    T. Tubiana, J.-C. Carvaillo, Y. Boulard, S. Bressanelli

    Journal of Chemical Information and Modeling 58(11), 2178–2182 (2018)

2017

  1. Membrane alterations induced by nonstructural proteins of human norovirus

    S. Doerflinger, M. Cortese, I. Romero-Brey, Z. Menne, T. Tubiana, C. Schenk, P. White, R. Bartenschlager, S. Bressanelli, G. Hansman, V. Lohmann

    PLOS Pathogens 13(10), e1006705 (2017)

  2. Dynamics and asymmetry in the dimer of the norovirus major capsid protein

    T. Tubiana, Y. Boulard, S. Bressanelli

    PloS One 12(7), e0182056 (2017)

  3. Dynamique d’assemblage de la capside des norovirus

    T. Tubiana

    (2017)

2015

  1. Three-dimensional representations of complex carbohydrates and polysaccharides—SweetUnityMol: A video game-based computer graphic software

    S. Pérez, T. Tubiana, A. Imberty, M. Baaden

    Glycobiology 25(5), 483–491 (2015)